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Cholesterol 25-hydroxylase protects against experimental colitis in mice by modulating epithelial gut barrier function
The key to success lies in consistency rather than excessive dosing
Studies have found that inhibiting KGDD activity due to mutations in IDH1/2, FH, or SDH increases sensitivity to DNA damaging agents, and the mechanisms described are due to changes in methylation (Inoue et al., 2016
KIM-1, as a specific and sensitive biomarker in the diagnosis of kidney injury, plays an important role in removing the cellular debris from the tubular lumen in renal injury
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